周小霞

博士，副研究员，硕士生导师

国家优秀青年基金获得者

广东省自然科学基金杰出青年基金获得者

“香江学者计划”入选者

广州市高层次人才

工作邮箱：xxzhou@soil.gd.cn

通讯地址：广州市天河区天源路808号

教育背景

2011.09−2016.07 中国科学院生态环境研究中心，分析化学，博士，导师：刘景富  研究员

2016.01−2016.05 美国佐治亚理工大学，访问学者，导师：陈勇生  教授

2007.09−2011.07 中国农业大学，化学，学士

工作经历

2024.10−今  广东省科学院生态环境与土壤研究所，副研究员

2018.08−2024.09 广州大学，大湾区环境研究院，副教授

2016.07−2018.07 中国科学院生态环境研究中心，博士后，合作导师：江桂斌  院士

研究方向

微纳米颗粒分析测定、纳米材料迁移转化与环境效应等

科研项目

[1] 国家自然科学基金优秀青年基金项目：纳米颗粒分析新方法与环境行为，2025/01−2027/12，200万，在研，主持。

[2] 国家自然科学基金面上项目：基于环境冠诱导萃取解析水稻土中纳米硫化镉生成与转化机制，2023/01−2026/12，53万，在研，主持。

[3] 国家自然科学基金面上项目：基于金属标记法定量研究水环境中微纳塑料的生物过程及其影响机制，2021/01−2024/12，61万，在研，主持。

[4] 广东省自然科学基金杰出青年项目：纳米环境地球化学，2023/01−2026/12，100万，在研，主持。

[5] 广东省自然科学基金面上项目：微纳塑料在典型水生生物中富集、净化及沿食物链传递过程研究，2021/01−2023/12，10万，在研，主持。

[6] 广州大学百人计划引进人才科研启动项目,水环境中微纳塑料的分析方法、转化机制和生物效应研究，2018/09−2023/08，100万，在研，主持。

[7] 粤港澳环境质量协同创新联合实验室开放基金：纳塑料在典型水生生物中的转运过程及其影响机制研究，2021/04−2022/03，5万，结题，主持。

[8] 国家自然科学基金青年基金：细胞培养基中纳米银形态的转化及其细胞毒性效应研究，2018/01−2020/12，25万，结题，主持。

[9] 中国博士后基金第61批面上资助项目：细胞暴露培养基中纳米银的形态转化研究，2017/05−2018/07，8万，结题，主持。

[10] 中国博士后基金第11批特等资助项目：水环境中微纳塑料的分离测定方法与环境行为研究，2018/05−2018/12，15万，结题，主持。

代表性论文

[1] Jia, C.^‖; Li, X. F.^‖; Hu, S.; Liu, G. H.; Fang, J. S.^*; Zhou, X. X.*; Yan, X. L.*; Yan, B. Advanced Mass-Spectra-Based Machine Learning for Predicting the Toxicity of Traditional Chinese Medicines. Analytical Chemistry, 2025, 97, 783–792. (中国 科学院一区，自然指数期刊 )

[2] Zhang, J.; Hou, X. F.; Zhang, K. N.; Xiao, Q. Z.; Gardea-Torresdey, J.; Zhou, X. X.*; Yan, B. Photochemistry of Microplastics-Derived Dissolved Organic Matter: Reactive Species Generation and Organic Pollutant Degradation. Water Research, 2025, 269, 122802. (中国科学院一区，自然指数期刊 )

[3] Zhou, X. X.^‖; Xiao, Q. Z.^‖; Zhang, K. N.; Gao, Y.; Zhang, J.; Fang, L. P.*; Yan, B. Li, F. B. Quantitatively Tracking the Speciation and Dynamics of Selenium Nanoparticles in Rice Plants. Analytical Chemistry, 2024, 96, 16937–16945. (中国科学院一区，自然指数期刊 )

[4] Zhou, Y. F.; Zhou, X. X.*; Jiang, H.; Liu, W. Z.; Chen, F. Y.; Gardea-Torresdey, J.; Yan, B. In Vitro Toxicity and Modeling Reveal Nanoplastic Effects on Marine Bivalves. ACS Nano, 2024, 18, 17228–17239. (中国科学院一区，自然指数期刊 )

[5] Zhou, Y. F.; Liu, W. Z.; Jiang, H.; Chen, F. Y.; Li, Y. P.; Gardea-Torresdey, J.; Zhou, X. X.*; Yan, B. Surface-Charge-Driven Ferroptosis and Mitochondrial Dysfunction Is Involved in Toxicity Diversity in the Marine Bivalve Exposed to Nanoplastics. ACS Nano, 2024, 18, 2370–2383. (中科院一区，自然指数期刊)

[6] Zhang, J.; Hou, X. F.; Zhang, K. N.; Deng, Y. W.; Xiao, Q. Z.; Zhou, X. X. *; Yan, B. Deciphering Fluorescent and Molecular Fingerprint of Dissolved Organic Matter Leached from Microplastics in Water. Water Research, 2024, 250, 121047. (中科院一区，自然指数期刊)

[7] Hao, T. W.; Gao, Y.; Li, Z. C.; Zhou, X. X.*; Yan, B. Size-Dependent Uptake and Depuration of Nanoplastics in Tilapia (Oreochromis niloticus) and Distinct Intestinal Impacts. Environmental Science & Technology, 2023, 57, 2804–2812. (中科院一区，自然指数期刊)

[8] Liu, X. G.; Fang, L. P.; Yan, X. L.; Gardea-Torresdey, J.; Gao, Y.; Zhou, X. X.; Yan, B. Surface Functional Groups and Biofilm Formation on Microplastics: Environmental Implications. Science of the Total Environment, 2023, 903, 166585. (中科院一区)

[9] Chi, H. Y.; Zhou, X. X.*; Wu, M. R.; Shan, W. Y.; Liu, J. F.; Wan, J. Q.; Yan, B.; Liu, R*. Regulating the Reaction Pathway of nZVI to Improve the Decontamination Performance through Magnetic Spatial Confinement Effect. Journal Hazardous Materials, 2023, 447, 130799. (中科院一区)

[10] Li, Y. J.^‖; Gao, Y.^‖; Jia, J. B.; Deng, Y. W.; Zhang, K. N.; Yan, B.; Zhou, X. X.* Protein Corona-induced Extraction Coupled to Fenton Oxidation for Selective and Nondestructive Preconcentration of Ag₂S Nanoparticles from Water. Water Research, 2022, 224, 119042. (中科院一区，自然指数期刊)

[11]  Li, Z. C.^‖; Gao, Y.^‖; Wu, Q. H.; Yan, B.; Zhou, X. X.* Quantifying the Occurrence of Polystyrene Nanoplastics in Environmental Solid Matrices via Pyrolysis-gas Chromatography/Mass Spectrometry. Journal of Hazardous Materials, 2022, 440, 129855. (中科院一区，JCR-Q1)

[12] Gao, Y.; Deng, Y. W.; Li, C. J.; Li, Z. C.; He, S.; Chi, H. Y.; Zhou, X. X.*; Yan, B. Simple Extraction and Ultrasensitive Determination of Nanoscale Silver from Environmental Waters. ACS Sustainable Chemistry & Engineering, 2022, 10, 1863−1870. (中科院一区，JCR-Q1)

[13]  He, S.; Chi, H. Y.; Li, C. J.; Gao, Y.; Li, Z. C.; Zhou, X. X.*; Yan, B. Distribution, Bioaccumulation, and Trophic Transfer of a Palladium-Doped Nanoplasctics in a Constructed Freshwater Ecosystem. Environmental Science: Nano, 2022, 9, 1353−1363. (中科院一区)

[14] Li, C. J.^‖; Gao, Y.^‖; He, S.; Chi, H. Y.; Li, Z. C.; Zhou, X. X.*; Yan, B.; Quantification of Nanoplastic Uptake in Cucumber Plants by Pyrolysis Gas Chromatography/Mass Spectrometry. Environmental Science & Technology Letters, 2021, 8, 633−638. (中科院一区)

[15] Zhou, X. X.; He, S.; Gao, Y.; Chi, H. Y.; Wang, D. J.; Li, Z. C.; Yan, B.* Quantitative Analysis of Polystyrene and Poly(methyl methacrylate)Nanoplastics in Tissues of Aquatic Animals. Environmental Science & Technology, 2021, 55, 3032−3040.  (中科院一区，自然指数期刊)

[16] Zhou, X. X.; He, S.; Gao, Y.; Li, Z. C.; Chi, H. Y.; Li, C. J.; Wang, D. J.; Yan, B.* Protein Corona-Mediated Extraction for Quantitative Analysis of Nanoplastics in Environmental Waters by Pyrolysis Gas Chromatography/Mass Spectrometry. Analytical Chemistry, 2021, 93, 6698−6705. (中科院一区，自然指数期刊)

[17]  Chi, H. Y.; Li, C. J.; Huang, M.; Wan, J. Q.*; Zhou, X. X.*; Yan. B. Targeted accumulation and spatial confinement effect of Fe(II)-MOFs@MIP for efficiently removing low concentration dibutyl phthalate, Chemical Engineering Journal, 2021, 424, 130367. (中科院一区)

[18] Chi, H. Y.; Wan, J. Q.; Zhou, X. X.*; Sun, J.; Yan, B. Fe@C activated peroxymonosulfate system for effectively degrading emerging contaminants: Analysis of the formation and activation mechanism of Fe coordinately unsaturated metal sites. Journal of Hazardous Materials. Journal of Hazardous Materials, 2021, 419, 126535. (中科院一区)

[19] Zhou, X. X.; Liu, R.; Hao, L. T.; Liu, J. F.* Identification of Polystyrene Nanoplastics Using Surface Enhanced Raman Spectroscopy. Talanta, 2021, 221, 121552. (中科院二区)

[20] Wang, D. J.; Yuan, X. R.; Jia, J. B.; He, S.; Zhou, X. X.*; Yan, B. Al³⁺ Reduces PM_2.5-Induced Cytotoxicity in Human Bronchial Epithelial Cells via Reducing ROS Production. Air Quality Atmosphere and Health, 2021, 14, 903−909. (中科院三区)

[21] Jiang, L. W.; He, S.; Wang, D. J.; Li, C. J.; Zhou, X. X.*; Yan, B. Polyvinylidene Fluoride Micropore Membrane for Removal of the Released Nanoparticles During the Application of Nanoparticle-Loaded Water Treatment Materials. Journal of Cleaner Production, 2020, 261, 121246. (中科院一区)

[22] Zhou, X. X.; Jiang, L. W.; Wang, D. J.; He, S.; Li, C. J.; Yan, B.* Speciation Analysis of Ag₂S and ZnS Nanoparticles at the ng/L Level in Environmental Waters by Cloud Point Extraction Coupled with LC-ICPMS. Analytical Chemistry, 2020, 92,  4765−4770. (中科院一区，自然指数期刊)

[23] Zhou, X. X.; Hao, L. T.; Wang, H. Y. Z.; Li, Y. J.; Liu, J. F.* Cloud-Point Extraction Combined with Thermal Degradation for Nanoplastic Analysis Using Pyrolysis Gas Chromatography-Mass Spectrometry. Analytical Chemistry, 2019, 91, 1785−1790. (中科院一区，自然指数期刊)

[24] Zhou, X. X.; Lai, Y. J.; Liu, R.; Li, S. S.; Xu, J. W.; Liu, J. F.* Polyvinylidene Fluoride Micropore Membranes as Solid Phase Extraction Disk for Preconcentration of Nanoparticulate Silver in Environmental Waters. Environmental Science & Technology, 2017, 51, 13816−13824. (中科院一区，自然指数期刊)

[25] Zhou, X. X.; Liu, J. F.*; Jiang, G. B. Elemental Mass Size Distribution for Characterization, Quantification and Identification of Trace Nanoparticles in Serum and Environmental Waters. Environmental Science & Technology, 2017, 51, 3892−3901. (中科院一区，自然指数期刊)

[26] Zhou, X. X.; Li, Y. J.; Liu, J. F.* Highly Efficient Removal of Silver-containing Nanoparticles by Aged Iron Oxide Magnetic Particles. ACS Sustainable Chemistry & Engineering, 2017, 5, 5468−5476. (中科院一区)

[27] Zhou, X. X.; Liu, J. F.* Research Advances in Separation and Determination of Metallic Nanomaterials in the Environment (in Chinese). Chinese Science Bulletin, 2017, 62, 2758−2769.

[28] Zhou, X. X.; Liu, J. F.*; Yuan, C. G.; Chen, Y. S.* Speciation Analysis of Silver Sulfide Nanoparticles in Environmental Waters by Magnetic Solid Phase Extraction. Journal of Analytical Atomic Spectrometry, 2016, 31, 2285−2292. (中科院二区)

[29] Zhou, X. X.; Liu, J. F.*; Geng, F. L. Speciation Analysis of Metal Oxide Nanoparticles and Their Ionic Counterparts in Water Samples by Size Exclusion Chromatography Coupled to ICP-MS. NanoImpact, 2016, 1, 13−20. (中科院二区)

[30] Zhou, X. X.; Liu, R.; Liu, J. F.* Rapid Chromatographic Separation of Dissoluble Ag(I) and Silver-containing Nanoparticles of 1-100 Nanometer in Antibacterial Products and Environmental Waters. Environmental Science & Technology, 2014, 48, 14516−14524. (中科院一区，自然指数期刊)

奖励荣誉

2022年度中国分析测试协会科学技术奖（CAIA 奖）一等奖（纳米材料分离测定及其生物效应分析方法，排名第一）

2018年度中国分析测试协会科学技术奖（CAIA 奖）一等奖（金属形态分析、识别与示踪方法及其应用，排名第六）